A collection of validated probes made available to the research community from academic and commercial sources. Probes are matched with a validated target and in many cases a negative control compound is included in the set. Patent limitations apply to this library.
Please contact Dr. Haim Barr, head of HTS platform
A collection of validated probes made available to the research community to selectively modulate and validate kinase targets. The collection is based upon the GSK published kinase inhibitor set. Patent limitations apply to this library.
Please contact Dr. Haim Barr, head of HTS platform
A collection of validated probes made available to the research community to selectively modulate epigenetic targets such as bromodomains, methyltransferases. Control compounds are available from the SGC. Patent limitations apply to this library.
Please contact Dr. Haim Barr, head of HTS platform
Selected by computational chemists to complement the WIS collection with broadest coverage and maximum diversity
Suggested experimental design for co-localization study
Please contact Dr. Haim Barr, head of HTS platform
Some compounds have been approved by the FDA.
Includes most Selleck inhibitors, APIs, natural products, and chemotherapeutic agents.
Structurally diverse, medicinally active, and cell permeable.
A unique collection of 144 natural products for high throughput screening (HTS) and high content screening (HCS).
Structurally diverse, bioactive, and cell permeable.
Please contact Dr. Haim Barr, head of HTS platform
The Spectrum Collection
The HitFinderTM Collection consists of 14,400 MayBridge Screening Compounds, selected to represent the diversity of the MayBridge Screening Collection using a clustering algorithm based on standard Daylight Fingerprints and Tanimoto similarity.
Drug-like compounds selected using diversity sorting from the combined file of HTS and Historical collections. All compounds within the set strictly conform to rules of Lipinski and Veber, and do not bear undesired reactive functional groups.
2014 collection – pure Natural Products MEGx, isolated from plants or microorganism, that are currently available in > 10 mg, purity > 85%
2012 collection – A collection of highly purified plant metabolites that is enriched in bioactivity
2014 collection – pure Natural Products MEGx, isolated from plants or microorganism, that are currently available in > 10 mg, purity > 85%
Drug-like compounds represented in the DIVERSet™ libraries are carefully selected to provide the broadest pharmacophore space coverage possible within a 50,000 compound set of diverse structures.
