SGC Donated probes

Size:
67

A collection of validated probes made available to the research community from academic and commercial sources. Probes are matched with a validated target and in many cases a negative control compound is included in the set. Patent limitations apply to this library.

Please contact Dr. Haim Barr, head of HTS platform

SGC Kineome probes

Size:
187

A collection of validated probes made available to the research community to selectively modulate and validate kinase targets. The collection is based upon the GSK published kinase inhibitor set. Patent limitations apply to this library.

Please contact Dr. Haim Barr, head of HTS platform

SGC Epigenetics probes

Size:
30

A collection of validated probes made available to the research community to selectively modulate epigenetic targets such as bromodomains, methyltransferases. Control compounds are available from the SGC. Patent limitations apply to this library.

Please contact Dr. Haim Barr, head of HTS platform

Diversity Library

Supplier:
Size:
100000

Selected by computational chemists to complement the WIS collection with broadest coverage and maximum diversity

DOFLA

Size:
8000

Suggested experimental design for co-localization study

Please contact Dr. Haim Barr, head of HTS platform

Bioactive Screening Libraries

Supplier:
Size:
1681

Some compounds have been approved by the FDA.

Includes most Selleck inhibitors, APIs, natural products, and chemotherapeutic agents.

Structurally diverse, medicinally active, and cell permeable.

Natural Product Library

Supplier:
Size:
144

A unique collection of 144 natural products for high throughput screening (HTS) and high content screening (HCS).

Structurally diverse, bioactive, and cell permeable.

Secretome (Secreted proteins)

Supplier:
Size:
300

Please contact Dr. Haim Barr, head of HTS platform

Spectrum Collection-Known Drugs (66%), Natural Products (26%) and Other Bioactive Components (8%)

Supplier:
Size:
2400

The Spectrum Collection

HitFinder® Collection

Supplier:
Size:
14400

The HitFinderTM Collection consists of 14,400 MayBridge Screening Compounds, selected to represent the diversity of the MayBridge Screening Collection using a clustering algorithm based on standard Daylight Fingerprints and Tanimoto similarity.

LOPAC

Supplier:
Size:
1280

Library of Pharmacologically Active Compounds.

Drug-Like Set (DLS)

Supplier:
Size:
20160

Drug-like compounds selected using diversity sorting from the combined file of HTS and Historical collections. All compounds within the set strictly conform to rules of Lipinski and Veber, and do not bear undesired reactive functional groups.

MEGxp: Pure natural compounds from plants

Supplier:
Size:
436

2014 collection – pure Natural Products MEGx, isolated from plants or microorganism, that are currently available in > 10 mg, purity > 85%

MEGxp: Pure natural compounds from plants

Supplier:
Size:
3540

2012 collection – A collection of highly purified plant metabolites that is enriched in bioactivity

MEGxm: Pure natural compounds from microorganisms

Supplier:
Size:
469

2014 collection – pure Natural Products MEGx, isolated from plants or microorganism, that are currently available in > 10 mg, purity > 85%

DIVERSet™-CL

Supplier:
Size:
50000

Drug-like compounds represented in the DIVERSet™ libraries are carefully selected to provide the broadest pharmacophore space coverage possible within a 50,000 compound set of diverse structures.