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Pan-cancer single-cell RNA-seq identifies recurring programs of cellular heterogeneity
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Structural basis for producing selective MAP2K7 inhibitors
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Ubiquitous selection for mecA in community-associated MRSA across diverse chemical environments
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MitoTimer-based high-content screen identifies two chemically-related benzothiophene derivatives that enhance basal mitophagy
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PRMT1 inhibition induces differentiation of colon cancer cells
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Covalent Docking Identifies a Potent and Selective MKK7 Inhibitor
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An Efficient One-Pot Enzymatic Synthesis of Cardiac Glycosides with Varied Sugar Chain Lengths
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Rapid Covalent-Probe Discovery by Electrophile-Fragment Screening
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The small molecule Chicago Sky Blue promotes heart repair following myocardial infarction in mice
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Targeting Spt5-Pol II by Small-Molecule Inhibitors Uncouples Distinct Activities and Reveals Additional Regulatory Roles
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Phenotypic Screen Identifies JAK2 as a Major Regulator of FAT10 Expression
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High content image analysis reveals function of miR-124 upstream of Vimentin in regulating motor neuron mitochondria
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Notch Activation by Shootin1 Opposing Activities on 2 Ubiquitin Ligases
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A multiplexed screening method for pluripotency
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Effective cell-free drug screening protocol for protein-protein interaction
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Protein recognition by a pattern-generating fluorescent molecular probe
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A Novel Allosteric Mechanism of NF-kappaB Dimerization and DNA Binding Targeted by an Anti-Inflammatory Drug.
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A generic, cost-effective, and scalable cell lineage analysis platform
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Digoxin derivatives with selectivity for the alpha2beta3 isoform of Na,K-ATPase potently reduce intraocular pressure.
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Synaptojanin 2 is a druggable mediator of metastasis and the gene is overexpressed and amplified in breast cancer