All Publications

  • SLAMF9 regulates pDC homeostasis and function in health and disease

    Sever L., Radomir L., Strim K. et al., Weiner A., Shchottlender N., Lewinsky H., Barak A. F., Friedlander G., Ben-Dor S., Becker-Herman S., Shachar I. (2019), Proceedings of the National Academy of Sciences of the United States of America. 116, 33, p. 16489-16496   |  All authors
  • The transcriptional profile of circulating myeloid derived suppressor cells correlates with tumor development and progression in mouse

    Nachmany I., Bogoch Y., Friedlander-Malik G. et al., Amar O., Bondar E., Zohar N., Hantisteanu S., Fainaru O., Lubezky N., Klausner J. M., Pencovich N. (2019), Genes and Immunity. 20, 7, p. 589-598   |  All authors
  • CSNAP, the smallest CSN subunit, modulates proteostasis through cullin-RING ubiquitin ligases

    Füzesi-Levi M. G., Fainer I., Ivanov Enchev R. et al., Ben-Nissan G., Levin Y., Kupervaser M., Friedlander G., Salame T. M., Nevo R., Peter M., Sharon M. (2019), Cell Death and Differentiation.   |  All authors
  • Transcriptome analysis highlights nuclear control of chloroplast development in the shoot apex

    Dalal V., Dagan S., Friedlander G. et al., Aviv E., Bock R., Charuvi D., Reich Z., Adam Z. (2018), Scientific Reports. 8, 8881   |  All authors
  • Pre-equilibrium competitive library screening for tuning inhibitor association rate and specificity toward serine proteases

    Cohen I., Naftaly S., Ben-Zeev E. et al., Hockla A., Radisky E. S., Papo N. (2018), Biochemical Journal. 475, p. 1335-1352   |  All authors
  • CD74 is a novel transcription regulator

    Gil-Yarom N., Radomir L., Sever L. et al., Kramer M. P., Lewinsky H., Bornstein C., Blecher-Gonen R., Barnett Itzhaki Z., Mirkin V., Friedlander G., Shvidel L., Herishanu Y., Lolis E. J., Becker Herman S., Amit I., Shachar I. (2017), Proceedings of the National Academy of Sciences of the United States of America. 114, 3, p. 562-567   |  All authors
  • Coordination of Meristem Doming and the Floral Transition by Late Termination, a Kelch Repeat Protein

    Tal L., Friedlander G., Gilboa N. S. et al., Unger T., Gilad S., Eshed Y. (2017), Plant Cell. 29, 4, p. 681-696   |  All authors
  • Seasonal heat stress affects adipose tissue proteome toward enrichment of the Nrf2-mediated oxidative stress response in late-pregnant dairy cows

    Zachut M., Kra G., Livshitz L. et al., Portnick Y., Yakoby S., Friedlander G., Levin Y. (2017), Journal of Proteomics. 158, p. 52-61   |  All authors
  • A computational combinatorial approach identifies a protein inhibitor of superoxide dismutase 1 misfolding, aggregation, and cytotoxicity

    Banerjee V., Oren O., Ben-Zeev E. et al., Taube R., Engel S., Papo N. (2017), Journal of Biological Chemistry. 292, 38, p. 15777-15788   |  All authors
  • The Ribosomal Protein uL22 Modulates the Shape of the Protein Exit Tunnel

    Wekselman I., Zimmerman E., Davidovich C. et al., Belousoff M., Matzov D., Krupkin M., Rozenberg H., Bashan A., Friedlander G., Kjeldgaard J., Ingmer H., Lindahl L., Zengel J. M., Yonath A. (2017), Structure with Folding & design. 25, 8, p. 1233-+   |  All authors
  • Using Synthetic Mouse Spike-In Transcripts to Evaluate RNA-Seq Analysis Tools

    Leshkowitz D., Feldmesser E., Friedlander G. et al., Jona G., Ainbinder E., Parmet Y., Horn-Saban S. (2016), PLoS One. 11, 4, e0153782   |  All authors
  • Prediction of homoprotein and heteroprotein complexes by protein docking and template-based modeling: A CASP-CAPRI experiment

    Lensink M. F., Velankar S., Kryshtafovych A. et al., Huang S., Schneidman-Duhovny D., Sali A., Segura J., Fernandez-Fuentes N., Viswanath S., Elber R., Grudinin S., Popov P., Neveu E., Lee H., Baek M., Park S., Heo L., Lee G. R., Seok C., Qin S., Zhou H., Ritchie D. W., Maigret B., Devignes M., Ghoorah A., Torchala M., Chaleil R. A. G., Bates P. A., Ben-Zeev E., Eisenstein M., Negi S. S., Weng Z., Vreven T., Pierce B. G., Borrman T. M., Yu J., Ochsenbein F., Guerois R., Vangone A., Rodrigues J. P. G. L. M., van Zundert Z. G., Nellen M., Xue L., Karaca E., Melquiond A. S. J., Visscher K., Kastritis P. L., Bonvin A. M. J. J., Xu X., Qiu L., Yan C., Li J., Ma Z., Cheng J., Zou X., Shen Y., Peterson L. X., Kim H., Roy A., Han X., Esquivel-Rodriguez J., Kihara D., Yu X., Bruce N. J., Fuller J. C., Wade R. C., Anishchenko I., Kundrotas P. J., Vakser I. A., Imai K., Yamada K., Oda T., Nakamura T., Tomii K., Pallara C., Romero-Durana M., Jimenez-Garcia B., Moal I. H., Fernandez-Recio J., Joung J. Y., Kim J. Y., Joo K., Lee J., Kozakov D., Vajda S., Mottarella S., Hall D. R., Beglov D., Mamonov A., Xia B., Bohnuud T., Del Capiro C. C. A., Ichiishi E., Marze N., Kuroda D., Burman S. S. R., Gray J. J., Chermak E., Cavallo L., Oliva R., Tovchigrechko A., Wodak S. J. (2016), Proteins-Structure Function And Bioinformatics. 84, p. 323-348   |  All authors
  • A Metabolic Gene Cluster in the Wheat W1 and the Barley Cer-cqu Loci Determines beta-Diketone Biosynthesis and Glaucousness

    Hen Avivi A. S., Savin O., Racovita R. C. et al., Lee W., Adamski N. M., Malitsky S., Almekias-Siegl E., Levy M., Vautrin S., Berges H., Friedlander G., Kartvelishvily E., Ben-Zvi G., Alkan N., Uauy C., Kanyuka K., Jetter R., Distelfeld A., Aharoni A. (2016), Plant Cell. 28, 6, p. 1440-1460   |  All authors
  • A Novel Allosteric Mechanism of NF-kappaB Dimerization and DNA Binding Targeted by an Anti-Inflammatory Drug.

    Ashkenazi S., Plotnikov A., Bahat A. et al., Ben-Zeev E., Warszawski S., Dikstein R. (2016), Molecular and Cellular Biology. 36, 8, p. 1237-47   |  All authors
  • Selective Assembly of Na,K-ATPase alpha(2)beta(2) Heterodimers in the Heart DISTINCT FUNCTIONAL PROPERTIES AND ISOFORM-SELECTIVE INHIBITORS

    Habeck M., Tokhtaeva E., Nadav Y. et al., Ben-Zeev E., Ferris S., Kaufman R., Bab-Dinitz E., Kaplan J., Dada L., Farfel Z., Tal D., Katz A., Sachs G., Vagin O., Karlish S. (2016), Journal of Biological Chemistry. 291, 44, p. 23159-23174   |  All authors
  • Digoxin derivatives with selectivity for the alpha 2 beta 3 isoform of Na,K-ATPase potently reduce intraocular pressure

    Heller D., Marcovich A., Katz A. et al., Tal D. M., Habeck M., Ben-Zeev E., Rabah B., Barkana Y., Karlish S. J. (2016),   |  All authors
  • Cap-independent translation by DAP5 controls cell fate decisions in human embryonic stem cells

    Kimchi A., Yoffe Y., David M. et al., Kalaora R., Povodovski L., Friedlander G., Feldmesser E., Ainbinder E. (2016), GENES & DEVELOPMENT. 30, 17, p. 1991-2004   |  All authors
  • Digoxin derivatives with selectivity for the alpha2beta3 isoform of Na,K-ATPase potently reduce intraocular pressure.

    Katz A., Tal D. M., Heller D. et al., Habeck M., Ben-Zeev E., Rabah B., Bar Kana K. Y., Marcovich A. L., Karlish S. J. (2015), Proceedings of the National Academy of Sciences of the United States of America. 112, 44, p. 13723-8   |  All authors
  • Simultaneous transcriptome analysis of Colletotrichum gloeosporioides and tomato fruit pathosystem reveals novel fungal pathogenicity and fruit defense strategies

    Alkan N., Friedlander G., Ment D. et al., Prusky D., Fluhr R. (2015), New Phytologist. 205, 2, p. 801-815   |  All authors
  • The Transcription and Translation Landscapes during Human Cytomegalovirus Infection Reveal Novel Host-Pathogen Interactions.

    Tirosh O., Cohen Y., Shitrit A. et al., Shani O., Le-Trilling V. T. K., Trilling M., Friedlander G., Tanenbaum M., Stern-Ginossar N. (2015), PLoS Pathogens. 11, 11, p. e1005288-e1005288, e1005288   |  All authors
  • Macrophage-Restricted Interleukin-10 Receptor Deficiency, but Not IL-10 Deficiency, Causes Severe Spontaneous Colitis

    Zigmond E., Bernshtein B., Friedlander G. et al., Walker C. R., Yona S., Kim K., Brenner O., Krauthgamer R., Varol C., Mueller W., Jung S. (2014), Immunity. 40, 5, p. 720-733   |  All authors
  • Divergent Levels of LBP and TGF beta 1 in Murine MSCs Lead to Heterogenic Response to TLR and Proinflammatory Cytokine Activation

    Levin S., Pevsner-Fischer M., Kagan S. et al., Lifshitz H., Weinstock A., Gataulin D., Friedlander G., Zipori D. (2014), Stem Cell Reviews. 10, 3, p. 376-388   |  All authors
  • Global Aspects of pacC Regulation of Pathogenicity Genes in Colletotrichum gloeosporioides as Revealed by Transcriptome Analysis

    Alkan N., Meng X., Friedlander G. et al., Reuveni E., Sukno S., Sherman A., Thon M., Fluhr R., Prusky D. (2013), Molecular Plant-Microbe Interactions. 26, 11, p. 1345-1358   |  All authors
  • Runx3-mediated Transcriptional Program in Cytotoxic Lymphocytes

    Lotem J., Levanon D., Negreanu V. et al., Leshkowitz D., Friedlander G., Groner Y. (2013), PLoS One. 8, 11   |  All authors
  • Mutant p53 Attenuates the Anti-Tumorigenic Activity of Fibroblasts- Secreted Interferon Beta

    Madar S., Harel E., Goldstein I. et al., Stein Y., Kogan-Sakin I., Kamer I., Solomon H., Dekel E., Tal P., Goldfinger N., Friedlander G., Rotter V. (2013), PLoS One. 8, 4   |  All authors
  • Failure of the Tomato Trans-Acting Short Interfering RNA Program to Regulate AUXIN RESPONSE FACTOR3 and ARF4 Underlies the Wiry Leaf Syndrome

    Yifhar T., Pekker I., Peled D. et al., Friedlander G., Pistunov A., Sabban M., Wachsman G., Alvarez J. P., Amsellem Z., Eshed Y. (2012), Plant Cell. 24, 9, p. 3575-3589   |  All authors
  • Ly6C(hi) Monocytes in the Inflamed Colon Give Rise to Proinflammatory Effector Cells and Migratory Antigen-Presenting Cells

    Zigmond E., Varol C., Farache J. et al., Elmaliah E., Satpathy A. T., Friedlander G., Mack M., Shpigel N., Boneca I. G., Murphy K. M., Shakhar G., Halpern Z., Jung S. (2012), Immunity. 37, 6, p. 1076-1090   |  All authors