All years20242023202220212020201920182017201620152014201320122011

All Publications

  • Large-scale proteomics analysis of five brain regions from Parkinsons disease patients with a GBA1 mutation

    Authors: Blumenreich S., Nehushtan T., Kupervaser M., Shalit T., Gabashvili A., Joseph T., Milenkovic I., Hardy J. & Futerman A. H. (2024), npj Parkinson's Disease. 10, 1, 33

  • Diversification of molecular pattern recognition in bacterial NLR-like proteins

    Authors: Béchon N., Tal N., Stokar-Avihail A., Savidor A., Kupervaser M., Melamed S., Amitai G. & Sorek R. (2024), Nature Communications. 15, 9860

  • Intracellular polarization of RNAs and proteins in the human small intestinal epithelium

    Authors: Novoselsky R., Harnik Y., Yakubovsky O., Katina C., Levin Y., Halpern K. B., Pencovich N., Nachmany I. & Itzkovitz S. (2024), PLoS Biology. 22, 12, e3002942

  • Loss-of-function cancer-linked mutations in the EIF4G2 non-canonical translation initiation factor

    Authors: Meril S., Bahlsen M., Eisenstein M., Savidor A., Levin Y., Bialik S., Pietrokovski S. & Kimchi A. (2024), Life Science Alliance. 7, 3, e202302338

  • Hypoxia-dependent recruitment of error-prone DNA polymerases to genome replication

    Authors: Yehuda R., Dromi I., Levin Y., Carell T., Geacintov N. & Livneh Z. (2024), Oncogene. 44, 1, p. 42-49, e104543

  • Proteomics analysis of the brain from a Gaucher disease mouse identifies pathological pathways including a possible role for transglutaminase 1

    Authors: Blumenreich S., Ben-Yashar D. P., Shalit T., Kupervaser M., Milenkovic I., Joseph T. & Futerman A. H. (2024), Journal of Neurochemistry. 168, 1, p. 52-65

  • VWD domain stabilization by autocatalytic Asp-Pro cleavage

    Authors: Yeshaya N., Gupta P. K., Dym O., Morgenstern D., Major D. T. & Fass D. (2024), Protein Science. 33, 3, e4929

  • PGR5-LIKE PHOTOSYNTHETIC PHENOTYPE1A redox states alleviate photoinhibition during changes in light intensity

    Authors: Chaturvedi A. K., Dym O., Levin Y. & Fluhr R. (2024), Plant Physiology. 194, 2, p. 1059-1074

  • Loss of EIF4G2 mediates aggressiveness in distinct human endometrial cancer subpopulations with poor survival outcome in patients

    Authors: Meril S., Muhlbauer Avni M., Lior C., Bahlsen M., Olender T., Savidor A., Krausz J., Belhanes Peled H., Birisi H., David N., Bialik S., Scherz-Shouval R., Ben David Y. & Kimchi A. (2024), Oncogene. 43, 15, p. 1098-1112

  • Genetic control over biogenic crystal morphogenesis in zebrafish

    Authors: Deis R., Lerer-Goldshtein T., Baiko O., Eyal Z., Brenman-Begin D., Goldsmith M., Kaufmann S., Heinig U., Dong Y., Lushchekina S., Varsano N., Olender T., Kupervaser M., Porat Z., Levin-Zaidman S., Pinkas I., Mateus R. & Gur D. (2024), Nature Chemical Biology. 21, 3, p. 383-392, 6368

  • A spatial expression atlas of the adult human proximal small intestine

    Authors: Harnik Y., Yakubovsky O., Hoefflin R., Novoselsky R., Bahar Halpern K., Barkai T., Korem Kohanim Y., Egozi A., Golani O., Addadi Y., Kedmi M., Keidar Haran T., Levin Y., Savidor A., Keren-Shaul H., Mayer C., Pencovich N., Pery R., Shouval D. S., Tirosh I., Nachmany I. & Itzkovitz S. (2024), Nature. 632, 8027, p. 1101-1109

  • BLM helicase protein negatively regulates stress granule formation through unwinding RNA G-quadruplex structures

    Authors: Danino Y. M., Molitor L., Rosenbaum-Cohen T., Kaiser S., Cohen Y., Porat Z., Marmor-Kollet H., Katina C., Savidor A., Rotkopf R., Ben-Isaac E., Golani O., Levin Y., Monchaud D., Hickson I. D. & Hornstein E. (2023), Nucleic Acids Research. 51, 17, p. 9369-9384

  • Large-Scale Immunopeptidome Analysis Reveals Recurrent Posttranslational Splicing of Cancer- and Immune-Associated Genes

    Authors: Levy R., Alter Regev T., Paes W., Gumpert N., Cohen Shvefel S., Bartok O., Dayan-Rubinov M., Alon M., Shmueli M., Levin Y., Merbl Y., Ternette N. & Samuels Y. (2023), Molecular and Cellular Proteomics. 22, 4, 100519

  • Molecular characterization of the intact mouse muscle spindle using a multi-omics approach

    Authors: Bornstein B., Heinemann-Yerushalmi L., Krief S., Adler R., Dassa B., Leshkowitz D., Kim M., Bewick G., Banks R. W. & Zelzer E. (2023), eLife. 12, e81843

  • Alpha-linolenic acid modulates systemic and adipose tissue-specific insulin sensitivity, inflammation, and the endocannabinoid system in dairy cows

    Authors: Kra G., Daddam J. R., Moallem U., Kamer H., Mualem B., Levin Y., Kočvarová R., Nemirovski A., Contreras A. G., Tam J. & Zachut M. (2023), Scientific Reports. 13, 1, 5280

  • Deciphering the involvement of the Hippo pathway co-regulators, YAP/TAZ in invadopodia formation and matrix degradation

    Authors: Venghateri J. B., Dassa B., Morgenstern D., Shreberk-Shaked M., Oren M. & Geiger B. (2023), Cell Death and Disease. 14, 4, 290

  • The proteasome regulator PSME4 modulates proteasome activity and antigen diversity to abrogate antitumor immunity in NSCLC

    Authors: Javitt A., Shmueli M. D., Kramer M. P., Kolodziejczyk A. A., Cohen I. J., Radomir L., Sheban D., Kamer I., Litchfield K., Bab-Dinitz E., Zadok O., Neiens V., Ulman A., Wolf-Levy H., Eisenberg-Lerner A., Kacen A., Alon M., Rêgo A. T., Stacher-Priehse E., Lindner M., Koch I., Bar J., Swanton C., Samuels Y., Levin Y., da Fonseca P. C., Elinav E., Friedman N., Meiners S. & Merbl Y. (2023), Nature Cancer. 4, 5, p. 629-647

  • The disulfide catalyst QSOX1 maintains the colon mucosal barrier by regulating Golgi glycosyltransferases

    Authors: Ilani T., Reznik N., Yeshaya N., Feldman T., Vilela P., Lansky Z., Javitt G., Shemesh M., Brenner O., Elkis Y., Varsano N., Jaramillo A. M., Evans C. M. & Fass D. (2023), The EMBO Journal. 42, 2, e111869

  • Redifferentiated cardiomyocytes retain residual dedifferentiation signatures and are protected against ischemic injury

    Authors: Shakked A., Petrover Z., Aharonov A., Ghiringhelli M., Umansky K., Kain D., Elkahal J., Divinsky Y., Nguyen P. D., Miyara S., Friedlander G., Savidor A., Zhang L., Perez D. E., Sarig R., Lendengolts D., Bueno-Levy H., Kastan N., Levin Y., Bakkers J., Gepstein L. & Tzahor E. (2023), Nature Cardiovascular Research. 2, 4, p. 383-398

  • Post-translational modifications reshape the antigenic landscape of the MHC I immunopeptidome in tumors

    Authors: Kacen A., Javitt A., Kramer M. P., Morgenstern D., Tsaban T., Shmueli M. D., Teo G. C., Leprevost F. d. V., Barnea E., Yu F., Admon A., Eisenbach L., Samuels Y., Schueler-Furman O., Levin Y., Nesvizhskii A. & Merbl Y. (2023), Nature Biotechnology. 41, 2, p. 239-251

  • Host transcriptome signatures in human faecal-washes predict histological remission in patients with IBD

    Authors: Ungar B., Yavzori M., Fudim E., Picard O., Kopylov U., Eliakim R., Shouval D., Levin Y., Savidor A., Ben-Moshe S., Manco R., Dan S., Egozi A., Bahar Halpern K., Mayer C., Barshack I., Ben-Horin S. & Itzkovitz S. (2022), Gut. 71, 10, p. 1988-1997

  • A new function for the serine protease HtrA2 in controlling radiation-induced senescence in cancer cells

    Authors: Hammer L., Levin-Salomon V., Yaeli-Slonim N., Weiss M., Dekel-Bird N. P., Olender T., Porat Z., Winograd-Katz S., Savidor A., Levin Y., Bialik S., Geiger B. & Kimchi A. (2022), Molecular Oncology. 16, 6, p. 1365-1383

  • Optimized Glycopeptide Enrichment Method-It Is All About the Sauce

    Authors: Morgenstern D., Wolf-Levy H., Tickotsky-Moskovitz N., Cooper I., Buchman A. S., Bennett D. A., Beeri M. S. & Levin Y. (2022), Analytical Chemistry. 94, 29, p. 10308-10313

  • Designed High-Redox Potential Laccases Exhibit High Functional Diversity

    Authors: Barber-Zucker S., Mateljak I., Goldsmith M., Kupervaser M., Alcalde M. & Fleishman S. J. (2022), ACS Catalysis. 12, 21, p. 13164-13173

  • Fatty acid transport protein 2 interacts with ceramide synthase 2 to promote ceramide synthesis

    Authors: Kim J. L., Mestre B., Malitsky S., Itkin M., Kupervaser M. & Futerman A. H. (2022), The journal of Biological chemistry. 298, 4, 101735

  • Utilization of diverse organophosphorus pollutants by marine bacteria

    Authors: Despotovic D., Aharon E., Trofimyuk O., Dubovetskyi A., Cherukuri K. P., Ashani Y., Eliason O., Sperfeld M., Leader H., Castelli A., Fumagalli L., Savidor A., Levin Y., Longo L., Segev E. & Tawfik D. (2022), Proceedings of the National Academy of Sciences of the United States of America. 119, 32, e220360411

  • Identification and characterization of the key enzyme in the biosynthesis of the neurotoxin β-ODAP in grass pea

    Authors: Goldsmith M., Barad S., Knafo M., Savidor A., Ben-Dor S., Brandis A., Mehlman T., Peleg Y., Albeck S., Dym O., Ben-Zeev E., Barbole R. S., Aharoni A. & Reich Z. (2022), The journal of Biological chemistry. 298, 5, 101806

  • Cross-talk between mutant p53 and p62/SQSTM1 augments cancer cell migration by promoting the degradation of cell adhesion proteins

    Authors: Mukherjee S., Maddalena M., Lü Y., Martinez S., Nataraj N. B., Noronha A., Sinha S., Teng K., Cohen-Kaplan V., Ziv T., Arandkar S., Hassin O., Chatterjee R., Pirona A., Shreberk-Shaked M., Gershoni A., Aylon Y., Elazar Z., Yarden Y., Schramek D. & Oren M. (2022), Proceedings of the National Academy of Sciences. 119, 17, e211964411

  • Co-Translational Membrane Targeting and Holo-Translocon Docking of Ribosomes Translating the SRP Receptor

    Authors: Mayer M., Winer L., Karniel A., Pinner E., Yardeni E. H., Morgenstern D. & Bibi E. (2022), Journal of Molecular Biology. 434, 5, 167459

  • SUMOylation of linker histone H1 drives chromatin condensation and restriction of embryonic cell fate identity

    Authors: Sheban D., Shani T., Maor R., Aguilera-Castrejon A., Mor N., Oldak B., Shmueli M. D., Eisenberg-Lerner A., Bayerl J., Hebert J., Viukov S., Chen G., Kacen A., Krupalnik V., Chugaeva V., Tarazi S., Rodríguez-delaRosa A., Zerbib M., Ulman A., Masarwi S., Kupervaser M., Levin Y., Shema E., David Y., Novershtern N., Hanna J. H. & Merbl Y. (2022), Molecular Cell. 82, 1, p. 106-122.e9

  • Comparison of matched formalin-fixed paraffin embedded and fresh frozen meningioma tissue reveals bias in proteomic profiles

    Authors: Schoffman H., Levin Y., Itzhaki-Alfia A., Tselekovits L., Gonen L., Vainer G. W., Hout-Siloni G., Barshack I., Cohen Z. R., Margalit N. & Shahar T. (2022), Proteomics. 22, 21, 2200085

  • DAP5 drives translation of specific mRNA targets with upstream ORFs in human embryonic stem cells

    Authors: David M., Olender T., Mizrahi O., Weingarten-Gabbay S., Friedlander G., Meril S., Goldberg N., Savidor A., Levin Y., Salomon V., Stern-Ginossar N., Bialik S. & Kimchi A. (2022), RNA. 28, 10, p. 1325-1336

  • Amniotic fluid biomarkers predict the severity of congenital cytomegalovirus infection

    Authors: Vorontsov O., Levitt L., Lilleri D., Vainer G. W., Kaplan O., Schreiber L., Arossa A., Spinillo A., Furione M., Alfi O., Oiknine-Djian E., Kupervaser M., Nevo Y., Elgavish S., Yassour M., Zavattoni M., Bdolah-Abram T., Baldanti F., Geal-Dor M., Zakay-Rones Z., Yanai N., Yagel S., Panet A. & Wolf D. G. (2022), The Journal of Clinical Investigation. 132, 11, e157415

  • Multiple phage resistance systems inhibit infection via SIR2-dependent NAD+ depletion

    Authors: Garb J., Lopatina A., Bernheim A., Zaremba M., Siksnys V., Melamed S., Leavitt A., Millman A., Amitai G. & Sorek R. (2022), Nature Microbiology. 7, 11, p. 1849-1856

  • Identification of bacteria-derived HLA-bound peptides in melanoma

    Authors: Kalaora S., Nagler A., Nejman D., Alon M., Barbolin C., Barnea E., Ketelaars S. L. C., Cheng K., Vervier K., Shental N., Bussi Y., Rotkopf R., Levy R., Benedek G., Trabish S., Dadosh T., Levin-Zaidman S., Geller L. T., Wang K., Greenberg P., Yagel G., Peri A., Fuks G., Bhardwaj N., Reuben A., Hermida L., Johnson S. B., Galloway-Peña J. R., Shropshire W. C., Bernatchez C., Haymaker C., Arora R., Roitman L., Eilam R., Weinberger A., Lotan-Pompan M., Lotem M., Levin Y., Lawley T. D., Adams D. J., Levesque M. P., Besser M. J., Schachter J., Golani O., Segal E., Ruppin E., Kvistborg P., Peterson S. N., Wargo J. A., Straussman R. & Samuels Y. (2021), Nature (London). 592, 7852, p. 138-143

  • Persistent Inflammatory Stimulation Drives the Conversion of MSCs to Inflammatory CAFs That Promote Pro-Metastatic Characteristics in Breast Cancer Cells

    Authors: Rubinstein-Achiasaf L., Morein D., Ben-Yaakov H., Liubomirski Y., Meshel T., Elbaz E., Dorot O., Pichinuk E., Gershovits M., Weil M. & Ben-Baruch A. (2021), Cancers. 13, 6, 1472

  • Anti-tumour immunity induces aberrant peptide presentation in melanoma

    Authors: Bartok O., Pataskar A., Nagel R., Laos M., Goldfarb E., Hayoun D., Levy R., Körner P., Kreuger I. Z. M., Champagne J., Zaal E. A., Bleijerveld O. B., Huang X., Kenski J., Wargo J., Brandis A., Levin Y., Mizrahi O., Alon M., Lebon S., Yang W., Nielsen M. M., Stern-Ginossar N., Altelaar M., Berkers C. R., Geiger T., Peeper D. S., Olweus J., Samuels Y. & Agami R. (2021), Nature. 590, 7845, p. 332-337

  • RawBeans: A Simple, Vendor-Independent, Raw-Data Quality-Control Tool

    Authors: Morgenstern D., Barzilay R. & Levin Y. (2021), Journal of Proteome Research. 20, 4, p. 2098-2104

  • Phosphoproteomic Analysis of Subcutaneous and Omental Adipose Tissue Reveals Increased Lipid Turnover in Dairy Cows Supplemented with Conjugated Linoleic Acid

    Authors: Daddam J. R., Hammon H. M., Tröscher A., Vogel L., Gnott M., Kra G., Levin Y., Sauerwein H. & Zachut M. (2021), International Journal of Molecular Sciences. 22, 6, 3227

  • Evolution of CPEB4 Dynamics across its Liquid-Liquid Phase Separation Transition

    Authors: Seal M., Jash C., Jacob R., Feintuch A., Harel Y., Albeck S., Unger T. & Goldfarb D. (2021), Journal Of Physical Chemistry B. 125, 47, p. 12947-12957

  • Anti-SARS-CoV-2 antibodies elicited by COVID-19 mRNA vaccine exhibit a unique glycosylation pattern

    Authors: Farkash I., Feferman T., Cohen-Saban N., Avraham Y., Morgenstern D., Mayuni G., Barth N., Lustig Y., Miller L., Shouval D. S., Biber A., Kirgner I., Levin Y. & Dahan R. (2021), Cell Reports. 37, 11, 110114

  • Uncovering deeply conserved motif combinations in rapidly evolving noncoding sequences

    Authors: Ross C. J., Rom A., Spinrad A., Gelbard-Solodkin D., Degani N. & Ulitsky I. (2021), Genome Biology. 22, 1, 29

  • Combined presentation and immunogenicity analysis reveals a recurrent RAS.Q61K neoantigen in melanoma

    Authors: Peri A., Greenstein E., Alon M., Pai J. A., Dingjan T., Reich-Zeliger S., Barnea E., Barbolin C., Levy R., Arnedo-Pac C., Kalaora S., Dassa B., Feldmesser E., Shang P., Greenberg P., Levin Y., Benedek G., Levesque M. P., Adams D. J., Lotem M., Wilmott J. S., Scolyer R. A., Jönsson G. B., Admon A., Rosenberg S. A., Cohen C. J., Niv M. Y., Lopez-Bigas N., Satpathy A. T., Friedman N. & Samuels Y. (2021), Journal of Clinical Investigation. 131, 20, e129466

  • Spatial discordances between mRNAs and proteins in the intestinal epithelium

    Authors: Harnik Y., Buchauer L., Ben-Moshe S., Averbukh I., Levin Y., Savidor A., Eilam R., Moor A. E. & Itzkovitz S. (2021), Nature metabolism. 3, 12, p. 1680-1693

  • A cyanobacterial component required for pilus biogenesis affects the exoproteome

    Authors: Yegorov Y., Sendersky E., Zilberman S., Nagar E., Ben-Asher H. W., Shimoni E., Simkovsky R., Golden S. S., Liwang A. & Schwarz R. (2021), mBio. 12, 2, 03674-20

  • Identification of presented SARS-CoV-2 HLA class I and HLA class II peptides using HLA peptidomics

    Authors: Nagler A., Kalaora S., Barbolin C., Gangaev A., Ketelaars S. L., Alon M., Pai J., Benedek G., Yahalom-Ronen Y., Erez N., Greenberg P., Yagel G., Peri A., Levin Y., Satpathy A. T., Bar-Haim E., Paran N., Kvistborg P. & Samuels Y. (2021), Cell reports (Cambridge). 35, 13, 109305

  • IRS1 phosphorylation underlies the non-stochastic probability of cancer cells to persist during EGFR inhibition therapy

    Authors: Jacob Berger A., Gigi E., Kupershmidt L., Meir Z., Gavert N., Zwang Y., Prior A., Gilad S., Harush U., Haviv I., Stemmer S. M., Blum G., Merquiol E., Mardamshina M., Kaminski Strauss S., Friedlander G., Bar J., Kamer I., Reizel Y., Geiger T., Pilpel Y., Levin Y., Tanay A., Barzel B., Reuveni H. & Straussman R. (2021), Nature Cancer. 2, 10, p. 1055-1070

  • A tecpr2 knockout mouse exhibits age-dependent neuroaxonal dystrophy associated with autophagosome accumulation

    Authors: Tamim-Yecheskel B., Fraiberg M., Kokabi K., Freud S., Shatz O., Marvaldi L., Subic N., Brenner O., Tsoory M., Eilam-Altstadter R., Biton I., Savidor A., Dezorella N., Heimer G., Behrends C., Ben-Zeev B. & Elazar Z. (2021), Autophagy. 17, 10, p. 3082-3095

  • SPEAR: A proteomics approach for simultaneous protein expression and redox analysis

    Authors: Doron S., Lampl N., Savidor A., Katina C., Gabashvili A., Levin Y. & Rosenwasser S. (2021), Free radical biology & medicine. 176, 20, p. 366-377

  • Proteomics analysis of a human brain sample from a mucolipidosis type IV patient reveals pathophysiological pathways

    Authors: Vardi A., Pri-Or A., Wigoda N., Grishchuk Y. & Futerman A. H. (2021), Orphanet Journal of Rare Diseases. 16, 1, 39

  • Immunoproteasome expression is associated with better prognosis and response to checkpoint therapies in melanoma

    Authors: Kalaora S., Lee J. S., Barnea E., Levy R., Greenberg P., Alon M., Yagel G., Bar Eli G., Oren R., Peri A., Patkar S., Bitton L., Rosenberg S. A., Lotem M., Levin Y., Admon A., Ruppin E. & Samuels Y. (2020), Nature Communications. 11, 1, 896

  • ERBB2 drives YAP activation and EMT-like processes during cardiac regeneration

    Authors: Aharonov A., Shakked A., Umansky K. B., Savidor A., Genzelinakh A., Kain D., Lendengolts D., Revach O. Y., Morikawa Y., Dong J., Levin Y., Geiger B., Martin J. F. & Tzahor E. (2020), Nature Cell Biology. 22, 11, p. 1346-1356

  • Loss of the Periplasmic Chaperone Skp and Mutations in the Efflux Pump AcrAB-TolC Play a Role in Acquired Resistance to Antimicrobial Peptides in Salmonella typhimurium

    Authors: Kapach G., Nuri R., Schmidt C., Danin A., Ferrera S., Savidor A., Gerlach R. G. & Shai Y. (2020), Frontiers in Microbiology. 11, 189

  • A Unified Linear Viscoelastic Model of the Cell Nucleus Defines the Mechanical Contributions of Lamins and Chromatin

    Authors: Wintner O., Hirsch-Attas N., Schlossberg M., Brofman F., Friedman R., Kupervaser M., Kitsberg D. & Buxboim A. (2020), Advanced Science. 7, 8, 1901222

  • CSNAP, the smallest CSN subunit, modulates proteostasis through cullin-RING ubiquitin ligases

    Authors: Fuzesi-Levi M. G., Fainer I., Enchev R. I., Ben-Nissan G., Levin Y., Kupervaser M., Friedlander G., Salame T. M., Nevo R., Peter M. & Sharon M. (2020), Cell Death and Differentiation. 27, 3, p. 984-998

  • Comparative Structural Analysis of 20S Proteasome Ortholog Protein Complexes by Native Mass Spectrometry

    Authors: Vimer S., Ben-Nissan G., Morgenstern D., Kumar-Deshmukh F., Polkinghorn C., Quintyn R. S., Vasil'ev Y. V., Beckman J. S., Elad N., Wysocki V. H. & Sharon M. (2020), ACS Central Science. 6, 4, p. 573-588

  • Novel Proteome Extraction Method Illustrates a Conserved Immunological Signature of MSI-H Colorectal Tumors.

    Authors: Vainer E. D., Kania-Almog J., Zatara G., Levin Y. & Vainer G. W. (2020), Molecular & Cellular Proteomics. 19, 10, p. 1619-1631

  • Efficient targeted degradation via reversible and irreversible covalent PROTACs

    Authors: Gabizon R., Shraga A., Gehrtz P., Livnah E., Shorer Y., Gurwicz N., Avram L., Unger T., Aharoni H., Albeck S., Brandis A., Shulman Z., Katz B., Herishanu Y. & London N. (2020), Journal of the American Chemical Society. 142, 27, p. 11734-11742

  • PRMT1 inhibition induces differentiation of colon cancer cells

    Authors: Plotnikov A., Kozer N., Cohen G., Carvalho S., Duberstein S., Almog O., Solmesky L. J., Shurrush K. A., Babaev I., Benjamin S., Gilad S., Kupervaser M., Levin Y., Gershovits M., Ben-Avraham D. & Barr H. M. (2020), Scientific Reports. 10, 1, 20030

  • Influence of short-term exposure to high light on photosynthesis and proteins involved in photo-protective processes in tomato leaves

    Authors: Bednarczyk D., Aviv-Sharon E., Savidor A., Levin Y. & Charuvi D. (2020), Environmental and Experimental Botany. 179, 104198

  • The coding capacity of SARS-CoV-2

    Authors: Finkel Y., Mizrahi O., Nachshon A., Weingarten-Gabbay S., Morgenstern D., Yahalom-Ronen Y., Tamir H., Achdout H., Stein D., Israeli O., Beth-Din A., Melamed S., Weiss S., Israely T., Paran N., Schwartz M. & Stern-Ginossar N. (2020), Nature. 589, 7840, p. 125-130

  • miR-17-92 and miR-106b-25 clusters regulate beta cell mitotic checkpoint and insulin secretion in mice

    Authors: Mandelbaum A. D., Kredo-Russo S., Aronowitz D., Myers N., Yanowski E., Klochendler A., Swisa A., Dor Y. & Hornstein E. (2019), Diabetologia. 62, 9, p. 1653-1666

  • Pro-inflammatory Cytokines Alter the Immunopeptidome Landscape by Modulation of HLA-B Expression

    Authors: Javitt A., Barnea E., Kramer M. P., Wolf-Levy H., Levin Y., Admon A. & Merbl Y. (2019), Frontiers in Immunology. 10, 10, 141

  • Proteomic analysis reveals greater abundance of complement and inflammatory proteins in subcutaneous adipose tissue from postpartum cows treated with sodium salicylate

    Authors: Takiya C. S., Montgomery S. R., Mamedova L. K., Kra G., Nemes-Navon N., Levin Y., Fleming S. D., Bradford B. J. & Zachut M. (2019), Journal of Proteomics. 204, 103399

  • Chlorophyll catabolism precedes changes in chloroplast structure and proteome during leaf senescence

    Authors: Tamary E., Nevo R., Naveh L., Levin-Zaidman S., Kiss V., Savidor A., Levin Y., Eyal Y., Reich Z. & Adam Z. (2019), Plant Direct. 3, 3, 127

  • UVB-Induced Tumor Heterogeneity Diminishes Immune Response in Melanoma

    Authors: Wolf Y., Bartok O., Patkar S., Eli G. B., Cohen S., Litchfield K., Levy R., Jiménez-Sánchez A., Trabish S., Lee J. S., Karathia H., Barnea E., Day C., Cinnamon E., Stein I., Solomon A., Bitton L., Pérez-Guijarro E., Dubovik T., Shen-Orr S. S., Miller M. L., Merlino G., Levin Y., Pikarsky E., Eisenbach L., Admon A., Swanton C., Ruppin E. & Samuels Y. (2019), Cell. 179, 1, p. 219-235

  • Proteome dataset of subcutaneous adipose tissue from postpartum cows treated with sodium salicylate

    Authors: Takiya C., Montgomery S., Mamedova L., Kra G., Nemes-Navon N., Levin Y., Fleming S., Bradford B. & Zachut M. (2019), Data in Brief. 26, 104567

  • Suspension Trapping (S-Trap) Is Compatible with Typical Protein Extraction Buffers and Detergents for Bottom-Up Proteomics

    Authors: Elinger D., Gabashvili A. & Levin Y. (2019), Journal of Proteome Research. 18, 3, p. 1441-1445

  • Unraveling essential cellulosomal components of the (Pseudo)Bacteroides cellulosolvens reveals an extensive reservoir of novel catalytic enzymes

    Authors: Zhivin-Nissan O., Dassa B., Morag E., Kupervaser M., Levin Y. & Bayer E. A. (2019), Biotechnology for Biofuels. 12, 115

  • Rapid characterization of secreted recombinant proteins by native mass spectrometry

    Authors: Ben-Nissan G., Vimer S., Warszawski S., Katz A., Yona M., Unger T., Peleg Y., Morgenstern D., Cohen-Dvashi H., Diskin R., Fleishman S. J. & Sharon M. (2018), Communications Biology. 1, 1, 213

  • Revealing the cellular degradome by mass spectrometry analysis of proteasome-cleaved peptides

    Authors: Wolf-Levy H., Javitt A., Eisenberg-Lerner A., Kacenl A., Ulman A., Sheban D., Dassa B., Fishbain-Yoskovitz V., Carmona-Rivera C., Kramer M. P., Nudel N., Regev I., Zahavi L., Elinger D., Kaplan M. J., Morgenstern D., Levin Y. & Merbl Y. (2018), Nature Biotechnology. 36, 11, p. 1110-1116

  • Neutralizing Gatad2a-Chd4-Mbd3/NuRD Complex Facilitates Deterministic Induction of Naive Pluripotency

    Authors: Mor N., Rais Y., Sheban D., Peles S., Aguilera-Castrejon A., Zviran A., Elinger D., Viukov S., Geula S., Krupalnik V., Zerbib M., Chomsky E., Lasman L., Shani T., Bayerl J., Gafni O., Hanna S., Buenrostro J. D., Hagai T., Masika H., Vainorius G., Bergman Y., Greenleaf W. J., Esteban M. A., Elling U., Levin Y., Massarwa R., Merbl Y., Novershtern N. & Hanna J. H. (2018), Cell Stem Cell. 23, 3, p. 412-425

  • The Xanthomonas euvesicatoria type III effector XopAU is an active protein kinase that manipulates plant MAP kinase signaling

    Authors: Teper D., Girija A. M., Bosis E., Popov G., Savidor A. & Sessa G. (2018), PLoS Pathogens. 14, 1, 1006880

  • CAPN1 is a novel binding partner and regulator of the tumor suppressor NF1 in melanoma

    Authors: Alon M., Arafeh R., Lee J. S., Madan S., Kalaora S., Nagler A., Abgarian T., Greenberg P., Ruppin E. & Samuels Y. (2018), Oncotarget. 9, 58, p. 31264-31277

  • The Disordered Landscape of the 20S Proteasome Substrates Reveals Tight Association with Phase Separated Granules

    Authors: Myers N., Olender T., Savidor A., Levin Y., Reuven N. & Shaul Y. (2018), Proteomics. 18, 21-22, 1800076

  • Characterization of the endocannabinoid system in subcutaneous adipose tissue in periparturient dairy cows and its association to metabolic profiles

    Authors: Zachut M., Kra G., Moallem U., Livshitz L., Levin Y., Udi S., Nemirovski A. & Tam J. (2018), PLoS ONE. 13, 11, 0205996

  • Triple-Stage Mass Spectrometry Unravels the Heterogeneity of an Endogenous Protein Complex

    Authors: Ben-Nissan G., Belov M. E., Morgenstern D., Levin Y., Dym O., Arkind G., Lipson G., Makarov A. A. & Sharon M. (2017), Analytical Chemistry. 89, 8, p. 4708-4715

  • Database-independent protein sequencing (DiPS) enables full-length de Novo protein and antibody sequence determination

    Authors: Savidor A., Barzilay R., Elinger D., Yarden Y., Lindzen M., Gabashvili A., Tal O. A. & Levin Y. (2017), Molecular & Cellular Proteomics. 16, 6, p. 1151-1161

  • The extracellular matrix protein agrin promotes heart regeneration in mice

    Authors: Bassat E., Mutlak Y. E., Genzelinakh A., Shadrin I. Y., Umansky K., Yifa O., Kain D., Rajchman D., Leach J., Bassat D. R., Udi Y., Sarig R., Sagi I., Martin J. F., Bursac N., Cohen S. & Tzahor E. (2017), Nature. 547, 7662, p. 179-184

  • Diadenosine tetraphosphate (Ap4A) an E. coli alarmone or a damage metabolite?

    Authors: Despotovic D., Brandis A., Savidor A., Levin Y., Fumagalli L. & Tawfik D. (2017), FEBS Journal. 284, 14, p. 2194-2215

  • BcXYG1, a secreted xyloglucanase from Botrytis cinerea, triggers both cell death and plant immune responses

    Authors: Zhu W., Ronen M., Gur Y., Minz-Dub A., Masrati G., Ben-Tal N., Savidor A., Sharon I., Eizner E., Valerius O., Braus G. H., Bowler K., Bar-Peled M. & Sharon A. (2017), Plant Physiology. 175, 1, p. 438-456

  • Principles of cellular resource allocation revealed by condition-dependent proteome profiling

    Authors: Metzl-Raz E., Kafri M., Yaakov G., Soifer I., Gurvich Y. & Barkai N. (2017), eLife. 6, e28034

  • Degradation of Bcl-2 by XIAP and ARTS Promotes Apoptosis

    Authors: Edison N., Curtz Y., Paland N., Mamriev D., Chorubczyk N., Haviv-Reingewertz T., Kfir N., Morgenstern D., Kupervaser M., Kagan J., Kim H. T. & Larisch S. (2017), Cell Reports. 21, 2, p. 442-454

  • Communication between viruses guides lysis-lysogeny decisions

    Authors: Erez Z., Steinberger-Levy I., Shamir M., Doron S., Stokar Avihail A. A., Peleg Y., Melamed S., Leavitt A., Savidor A., Albeck S., Amitai G. & Sorek R. (2017), Nature. 541, 7638, p. 488-493

  • Seasonal heat stress affects adipose tissue proteome toward enrichment of the Nrf2-mediated oxidative stress response in late-pregnant dairy cows

    Authors: Zachut M., Kra G., Livshitz L., Portnick Y., Yakoby S., Friedlander G. & Levin Y. (2017), Journal of Proteomics. 158, p. 52-61

  • Label-free deep shotgun proteomics reveals protein dynamics during tomato fruit tissues development

    Authors: Szymanski J., Levin Y., Savidor A., Breitel D., Chappell-Maor L., Heinig U., Toepfer N. & Aharoni A. (2017), Plant Journal. 90, 2, p. 396-417

  • The genetic basis for the adaptation of E-coli to sugar synthesis from CO2

    Authors: Herz E., Antonovsky N., Bar-On Y., Davidi D., Gleizer S., Prywes N., Noda-Garcia L., Frisch K. L., Zohar Y., Wernick D. G., Savidor A., Barenholz U. & Milo R. (2017), Nature Communications. 8, 1, 1705

  • Dynamics of hippocampal protein expression during long-Term spatial memory formation

    Authors: Borovok N., Nesher E., Levin Y., Reichenstein M., Pinhasov A. & Michaelevski I. (2016), Molecular & Cellular Proteomics. 15, 2, p. 523-541

  • Sugar Synthesis from CO2 in Escherichia coli

    Authors: Antonovsky N., Gleizer S., Noor E., Zohar Y., Herz E., Barenholz U., Zelcbuch L., Amram S., Wides A., Tepper N., Davidi D., Bar-On Y., Bareia T., Wernick D. G., Shani I., Malitsky S., Jona G., Bar-Even A. & Milo R. (2016), Cell. 166, 1, p. 115-125

  • Small secreted proteins enable biofilm development in the cyanobacterium Synechococcus elongatus.

    Authors: Parnasa R., Nagar E., Sendersky E., Reich Z., Simkovsky R., Golden S. & Schwarz R. (2016), Scientific Reports. 6, 32209

  • Distinct biological events generated by ECM proteolysis by two homologous collagenases

    Authors: Solomonov I., Zehorai E., Talmi-Frank D., Wolf S. G., Shainskaya A., Zhuravlev A., Kartvelishvily E., Visse R., Levin Y., Kampf N., Jaitin D. A., David E., Amit I., Nagase H. & Sagi I. (2016), Proceedings of the National Academy of Sciences of the United States of America. 113, 39, p. 10884-10889

  • Adipose-induced retroperitoneal soft tissue sarcoma tumorigenesis: A potential crosstalk between sarcoma and fat cells

    Authors: Loewenstein S., Lubezky N., Nizri E., Zemel M., Levin Y., Savidor A., Sher O., Klausner J. & Lahat G. (2016), Molecular Cancer Research. 14, 12, p. 1254-1265

  • Cross-linking reveals laminin coiled-coil architecture

    Authors: Armony G., Jacob E., Moran T., Levin Y., Mehlman T., Levy Y. & Fass D. (2016), Proceedings of the National Academy of Sciences of the United States of America. 113, 47, p. 13384-13389

  • Chronic Iron Limitation Confers Transient Resistance to Oxidative Stress in Marine Diatoms

    Authors: van Creveld C. S., Rosenwasser S., Levin Y. & Vardi A. (2016), Plant Physiology. 172, 2, p. 968-979

  • Proteomic analysis of preovulatory follicular fluid reveals differentially abundant proteins in less fertile dairy cows

    Authors: Zachut M., Sood P., Levin Y. & Moallem U. (2016), Journal of Proteomics. 139, p. 122-129

  • In planta anthocyanin degradation by a vacuolar class III peroxidase in Brunfelsia calycina flowers

    Authors: Zipor G., Duarte P., Carqueijeiro I., Shahar L., Ovadia R., Teper-Bamnolker P., Eshel D., Levin Y., Doron-Faigenboim A., Sottomayor M. & Oren-Shamir M. (2015), NEW PHYTOLOGIST. 205, 2, p. 653-665

  • Identification of a biomarker in cerebrospinal fluid for neuronopathic forms of Gaucher disease

    Authors: Zigdon H., Savidor A., Levin Y., Meshcheriakova A., Schiffmann R. & Futerman A. H. (2015), PLoS ONE. 10, 3, e0120194

  • Synapsin IIb as a functional marker of submissive behavior

    Authors: Nesher E., Koman I., Gross M., Tikhonov T., Bairachnaya M., Salmon-Divon M., Levin Y., Gerlitz G., Michaelevski I., Yadid G. & Pinhasov A. (2015), Scientific Reports. 5, 10287

  • MS1-based label-free proteomics using a quadrupole orbitrap mass spectrometer

    Authors: Shalit T., Elinger D., Savidor A., Gabashvili A. & Levin Y. (2015), Journal of Proteome Research. 14, 4, p. 1979-1986

  • CSNAP Is a Stoichiometric Subunit of the COP9 Signalosome

    Authors: Rozen S., Fuzesi-Levi M. G., Ben-Nissan G., Mizrachi L., Gabashvili A., Levin Y., Ben-Dor S., Eisenstein M. & Sharon M. (2015), Cell Reports. 13, 3, p. 585-598, 2073

  • Dysregulated miRNA biogenesis downstream of cellular stress and ALS-causing mutations: A new mechanism for ALS

    Authors: Emde A., Eitan C., Liou L., Libby R. T., Rivkin N., Magen I., Reichenstein I., Oppenheim H., Eilam R., Silvestroni A., Alajajian B., Ben-Dov I. Z., Aebischer J., Savidor A., Levin Y., Sons R., Hammond S. M., Ravits J. M., Moller T. & Hornstein E. (2015), The EMBO Journal. 34, 21, p. 2633-2651

  • Microbiota-Modulated Metabolites Shape the Intestinal Microenvironment by Regulating NLRP6 Inflammasome Signaling

    Authors: Levy M., Thaiss C. A., Zeevi D., Dohnalova L., Zilberman-Schapira G., Mahdi J. A., David E., Savidor A., Korem T., Herzig Y., Pevsner-Fischer M., Shapiro H., Christ A., Harmelin A., Halpern Z., Latz E., Flavell R. A., Amit I., Segal E. & Elinav E. (2015), Cell. 163, 6, p. 1428-1443

  • Disturbance of the bacterial cell wall specifically interferes with biofilm formation

    Authors: Bucher T., Oppenheimer-Shaanan Y., Savidor A., Bloom-Ackermann Z. & Kolodkin-Gal I. (2015), Environmental Microbiology Reports. 7, 6, p. 990-1004

  • Identification of the algal dimethyl sulfide-releasing enzyme: A missing link in the marine sulfur cycle

    Authors: Alcolombri U., Ben-Dor S., Feldmesser E., Levin Y., Tawfik D. & Vardi A. (2015), Science. 348, 6242, p. 1466-1469

  • Drift time-specific collision energies enable deep-coverage data-independent acquisition proteomics

    Authors: Distler U., Kuharev J., Navarro P., Levin Y., Schild H. & Tenzer S. (2014), Nature Methods. 11, 2, p. 167-170

  • Mapping the diatom redox-sensitive proteome provides insight into response to nitrogen stress in the marine environment

    Authors: Rosenwasser S., van Creveld C. S. G., Schatz D., Malitsky S., Tzfadia O., Aharoni A., Levin Y., Gabashvili A., Feldmesser E. & Vardi A. (2014), Proceedings of the National Academy of Sciences of the United States of America. 111, 7, p. 2740-2745

  • Dynamic regulation of the COP9 signalosome in response to DNA damage

    Authors: Fuzesi-Levi M. G., Ben-Nissan G., Bianchi E., Zhou H., Deery M. J., Lilley K. S., Levin Y. & Sharon M. (2014), Molecular and Cellular Biology. 34, 6, p. 1066-1076

  • Changes in atmospheric CO2 influence the allergenicity of Aspergillus fumigatus

    Authors: Lang Yona N., Levin Y., Dannemiller K. C., Yarden O., Peccia J. & Rudich Y. (2013), Global Change Biology. 19, 8, p. 2381-2388

  • Chimeras taking shape: Potential functions of proteins encoded by chimeric RNA transcripts

    Authors: Frenkel-Morgenstern M., Lacroix V., Ezkurdia I., Levin Y., Gabashvili A., Prilusky J., del Pozo P. A., Tress M., Johnson R., Guigo R. & Valencia A. (2012), Genome Research. 22, 7, p. 1231-1242

  • Analysis of the rat hypothalamus proteome by data-independent label-free LC-MS/MS

    Authors: Stelzhammer V., Amess B., Martins-de-Souza D., Levin Y., Ozanne S. E., Martin-Gronert M. S., Urday S., Bahn S. & Guest P. C. (2012), Proteomics. 12, 22, p. 3386-3392

  • Design and Application of a Data-Independent Precursor and Product Ion Repository

    Authors: Thalassinos K., Vissers J. P. C., Tenzer S., Levin Y., Thompson J. W., Daniel D., Mann D., DeLong M. R., Moseley M. A., America A. H., Ottens A. K., Cavey G. S., Efstathiou G., Scrivens J. H., Langridge J. I. & Geromanos S. J. (2012), Journal of the American Society for Mass Spectrometry. 23, 10, p. 1808-1820

  • Quantification of proteins using data-independent analysis (MS E) in simple andcomplex samples: A systematic evaluation

    Authors: Levin Y., Hradetzky E. & Bahn S. (2011), Proteomics. 11, 16, p. 3273-3287

  • Efficiency in complexity: Composition and dynamic nature of mimivirus replication factories

    Authors: Fridmann-Sirkis, Y.; Milrot, E.; Mutsafi, Y.; Ben-Dor, S.; Levin, Y.; Savidor, A.; Kartvelishvily, E.; Minsky, A. (), . 90, 21, p. 10039-10047