Working with chemical probs
The objective of G-INCPM is to identify chemical probes to help validate novel biological targets and their role in human diseases. Such Chemical probes can also serve as starting points for drug discovery efforts. The Medicinal chemistry group applys novel chemo informatics tools in the triage of hits from High Throughput Screening (HTS) and optimizing them towards chemical probes.
Chemical Probe are a selective small-molecule modulator of a protein’s function that allows the user to ask fundamental biological questions about its molecular target and its relevance to human diseases.